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Technologies Available for Licensing

Duquesne University offers new technologies developed in our laboratories for licensing. Individuals or organizations interested in pursuing the following technology transfer opportunities should contact the Office of Research at 412.396.6326, or volk@duq.edu .

Life Sciences

Pyrimidine Antitumor Drugs

Multiple acting anti-angiogenic and cytotoxic compounds

Implantable Non-Enzymatic Electrochemical Glucose Sensor

The technology is a non-enzymatic implantable glucose blood detector that makes use of a non-reactive tin oxide semiconductor measurement electrode and that is suitably energized by an electrical power source. Variations in current density at the measurement electrode are related to variations in glucose content of blood. The device also uses variable voltage to allow the electrode to be self-cleaning. U.S. patents 5,387,327 and 5,469,846.

Production Method for Vaccines against Biological Warfare Agents Methods for Eliciting an Immune Response to Bacterial Infections.

Time-Release Drug Formulations

The technology relates to the preparation of very small size, prolonged-release microcapsules of drugs that can be used as a suspension. The dosage form allows for dose adjustment and ease of swallowing, for example diclofenac sodium, especially in geriatric and pediatric populations. US Patent No. 6,156,340.

Computer Technology

Software for Authorship Identification and Screening

The technology is a novel software program using a method for document classification based on stylistic similarity, content and keywords,that can be used to select or filter e-mail, web sites or documents. A pilot version of the program is available for demonstration. U.S. Patent 6,397,205.

Real-time Computer Protection from Malicious Software

X-Ray Technology

Combined Differential Scanning Calorimetry and X-Ray Diffraction Analysis Instrument

The instrument allows to apply a new technique for performing simultaneous Differential Scanning Calorimetry and combined X-Ray diffraction analysis of a sample. The new instrument does not need housing in an insolated environment and can be provided as a desktop instrument, which uses 120 volt power, and which does not have the hazardous potential associated with the current technology. T his improvement opens up an area of analysis that could not be addressed before using the prior technology, and thus substantially expands the applications for using combined X_Ray Diffraction analysis with Differential Scanning Calorimetry analysis. The instrument allows the simultaneous structural characterization (XRD) of solid materials during a thermal (DSC) experiment and is able to directly record solid-state structural changes, melting, re-crystallization and dehydration measurements while simultaneously obtaining heat flow (calorimetry) data from a sample. U.S. Patent 4,821,303

Renewable Energy

Photochemical Hydrogen Production

An efficient photochemical hydrogen production technology allows to split water in the presence of sun light into hydrogen and oxygen using a chemically modified titanium dioxide electrode. The technology, which is currently at the laboratory stage, offers a photo-conversion efficiency above 10%. The titanium dioxide electrode is modified by introducing carbon into its structure which lowers the band-gap from 3.0 eV to 2.3 eV, allowing solar light absorption well into the visible spectrum. U.S. patent pending.

Manufacturing

Spectroscopic Verification and Inspection System for Drugs

The technology is integrated with an automated counting and dispensing device to allow for the chemical analysis of each dosage unit that is counted into a container or prescription vial. The counting and chemical verification happen simultaneously and the identity of each dosage unit is verified as its chemical and physical properties are expressed in a vibrational or electronic spectrum of the dosage unit. U.S. patent pending.

Apparatus for Inspecting Coated Drugs using Near-Infrared Spectroscopy

The technology allows for the inspection and quality control during the manufacturing process of the coating of each dosage unit by means of reflected near-infrared spectroscopy. U.S. patent 5,750,996

Comments and/or questions regarding the above information should be directed to the Office of Research at 412.396.6326.